A client has developed physical dependence on an opioid drug for pain relief. Which of the following interventions is appropriate first? 1. Immediately discontinue all drug therapy. 2. Replace the...

A client has developed physical dependence on an opioid drug for pain relief. Which of the following interventions is appropriate first?

1. Immediately discontinue all drug therapy.

2. Replace the opioid with a nonopioid drug.

3. Gradually decrease the dosage and frequency of the opioid.

4. Increase the dosage but decrease the frequency of the opioid.