A.The development of chronic pain is due in part to the sensitization of dorsal horn neurones. Which of the following receptors is thought to play a central role in this process? a. AMPA b. GABA c....

A.The development of chronic pain is due in part to the sensitization of dorsal horn neurones. Which of the following receptors is thought to play a central role in this process? a. AMPA b. GABA c. Kainate d. NMDA e. TRPV1 B. A 50-year-old female is admitted to the ICU from the Emergency Department with acute liver failure. She has taken an overdose of 50 grams of paracetamol 24 hours previously. She has been adequately fluid resuscitated since admission. Which of the following criteria would make her a candidate for super-urgent liver transplantation? a. Prothrombin time >100 seconds irrespective of the grade of encephalopathy b. Age >40 years, prothrombin time >50 seconds and serum bilirubin >308 µmol/l c. Prothrombin time >100 seconds and serum creatinine >301 µmol/l d. Arterial pH e. Arterial pH