All topics and their key points listed below must be discussed in your essay
Topic 1: Reproduction (10 marks total)
Endometrial tissue contains glandular structures relevant to Eshma’s reproductive function. Explain the role
of this glandular tissue in reproductive function, including any likely changes from normal in the secretion
and resultant effects for Eshma. (4 marks)
Considering Eshma and her current circumstances, describe the role of oestrogen and explain whether you
expect her oestrogen levels to be different to normal. Your discussion should include the homeostatic
regulation of female reproductive physiology and the relevant glands and hormones. (6 marks)
Topic 2: Respiratory system (5 marks total)
Describe the changes in volume and pressure that will be occurring in Eshma’s chest cavity during exhalation
on a long run. Explain why these changes are occurring, and the effect upon airflow. (5 marks)
Topic 3: Digestion/metabolism (8 marks total)
Eshma supplements her diet with a daily protein shake after exercise. Today though, Eshma is experiencing
some discomfort with indigestion, so takes a dose of Gaviscon® Dual Action soon after drinking her shake.
Discuss how taking Gaviscon® Dual Action could affect digestion of the protein in her shake. (4.5 marks)
State the hormone that is MOST active in maintaining Eshma’s blood glucose levels during a marathon.
Explain your answer. (3.5 marks)
Topic 4: Pharmacology (7 marks total)
In the past Eshma has used
Voltaren Emulgel
(containing an NSAID) to ease her aching muscles after
exercise. However, a friend has mentioned that Voltaren is also available in tablet form and may be better
for the “task”.
Compare and contrast the two different formulations of Voltaren available to Esham. In your answer you will
need to examine the following: (7 marks)
Where the drug is likely to be absorbed in each form
Likely bioavailability of each form and susceptibility to hepatic first pass effect
Why would the oral form be better?