For this assignment, your instructor will provide you with an epidemiological research article to review. Using the information in Chapter 14 of the textbook as a guide, summarize and critique the...

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For this assignment, your instructor will provide you with an epidemiological research article to review. Using the information in Chapter 14 of the textbook as a guide, summarize and critique the article based on the epidemiological methods and concepts covered in the course. By Day 7 Once you have reviewed the article, click the Module 6 Article Critique tab. You will be given a set of 15 randomly-selected questions to answer. These questions are short answer questions about the critique of the article. You will have 3 hours from the time you open your critique questions until you must have the answers submitted in Blackboard. While you may open and close the questions in Blackboard, the timer will not stop once it is started. You may complete the questions any time during Module 6, and they must be completed and submitted before the end of Module 6 (and within 3 hours of when you opened them). Make sure to answer in complete sentences and address all parts of each question. These questions will be worth 5 points each, for a total of 75 points. They will be graded by your instructor and partial credit is possible. Please see the article critique oup_ajepid_kwx170 1049..1056 ++ American Journal of Epidemiology © The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected]. Vol. 186, No. 9 DOI: 10.1093/aje/kwx170 Advance Access publication: May 23, 2017 Original Contribution Sex Differences in the Association Between Pain and Injurious Falls in Older Adults: A Population-Based Longitudinal Study Anna-KarinWelmer*, Debora Rizzuto, Amaia Calderón-Larrañaga, and Kristina Johnell *Correspondence to Dr. Anna-KarinWelmer, Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Gävlegatan 16, S-113 30 Stockholm, Sweden (e-mail: [email protected]). Initially submitted September 14, 2016; accepted for publication December 20, 2016. We investigated whether there are sex differences in the association between pain and incident injurious falls. A total of 2,934 people (ages ≥60 years) from the population-based Swedish National Study on Aging and Care in Kungsholmen (2001–2004) participated. Participants were followed up for 3 and 10 years for falls leading to hospi- talization or outpatient care. Data were analyzed with flexible parametric survival models that adjusted for potential confounders. During the first 3 years of follow-up, 67 men and 194 women experienced an injurious fall, and over 10 years of follow up, 203 men and 548 women experienced such a fall. In men, the presence of pain, having pain that was at least mild, having pain that affected several daily activities, and having daily pain all significantly increased the likelihood of incurring an injurious fall during the 3-year follow-up period. The multivariate-adjusted hazard ratios ranged from 1.78 (95% confidence interval: 1.00, 3.15) for the presence of pain to 2.89 (95% confi- dence interval: 1.41, 5.93) for several daily activities’ being affected by pain. Results for the 10-year follow-up period were similar. No significant associations were detected in women. Although pain is less prevalent in men than in women, its impact on risk of injurious falls seems to be greater in men. aged; falls; injury; pain; sex factors Abbreviation: SD, standard deviation. Injurious falls are a major public health concern and are associated with risk of disability, nursing home admissions, and death in older people. They also lead to considerable costs for society (1). Injurious falls have been associated with higher risk of disability and nursing home admissions than other conditions (e.g., diseases) that lead to hospitalization (2). The prevention of injurious falls should therefore be a high prior- ity in society. Successful preventive interventions depend on identifying and managing risk factors for falls. Pain is common in the older population and is a major cause of mobility limitation and disability (3–5). Studies of older adults have shown that pain also increases the likelihood of falls (4, 6–11). However, few studies have investigated whether the increased risk of falls in older people with pain also translates to an increased risk of fall-related injuries. One study found that pain of at least moderate intensity increased the likelihood of falls but not fractures in older men (12). Another study suggested that widespread pain of moderate-to-high intensity was associated with falls and fractures in older women with disabilities (7). Previous studies have shown that the incidence of (13), risk factors for (14, 15), and consequences of (16) falls may differ in men and women. For instance, older women fall more fre- quently than older men and have a higher risk of experiencing injurious falls, possibly because older women have poorer physi- cal function and a higher prevalence of osteoporosis than older men (13, 16). In addition, studies have shown that the prevalence of pain is higher in women than in men (17, 18) and that women may be more likely than men to experience severe pain (19). However, studies have not yet established whether the association between pain and injurious falls differs in older men and women (8). Therefore, our objective in this study was to examine whether there were sex differences in the associations between pain charac- teristics (location, intensity, frequency, and interference with daily activities) and incident injurious falls in older adults during short (3 years) and long (10 years) periods of observation. 1049 Am J Epidemiol. 2017;186(9):1049–1056 http://creativecommons.org/licenses/by-nc/4.0 http://creativecommons.org/licenses/by-nc/4.0 METHODS Study population Participants comprised people aged 60 years or older from a population-based study, the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K) (20). The study used stratified sampling. The population of Kungsholmen, an island in central Stockholm, was first stratified by age, and then a random sample of individuals was selected from each age cohort. A total of 11 age cohorts were chosen, with 6-year in- tervals between the younger cohorts (ages 60, 66, and 72 years) and 3-year intervals between the older cohorts (ages 78, 81, 84, 87, 90, 93, 96, and ≥99 years). Baseline data were collected from 2001 through 2004. A total of 5,111 people were initially selected to participate. Two hundred died before the start of the study, contact infor- mation was unavailable for 262 people, 32 had moved, 23 did not speak Swedish, and 4 were deaf. Of the remaining 4,590 people, 3,363 (73.3%) participated in the baseline examina- tion. In this study, we excluded an additional 349 people who had dementia (diagnosed in accordance with the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria) or who lived in an institution, because self-reported pain is difficult to measure in these groups (21). Of the remain- ing 3,014 people, pain questionnaire data were missing for 35 and outcome data for 45. The analytical sample (n = 2,934) was significantly younger (mean age = 73.1 (standard devi- ation (SD), 10.3) years vs. mean age = 86.3 (SD, 10.2) years; P < 0.01)="" than="" the="" group="" of="" eligible="" nonparticipants="" and="" included="" fewer="" women="" (62.6%women="" vs.="" 80.2%women;="" p="">< 0.01). the swedish national study on aging and care in kung- sholmen was approved by the regional ethical review board in stockholm, sweden. written informed consent was col- lected from participants. if the person could not answer (e.g., was cognitively impaired), consent was obtained from a proxy (usually a close family member). data collection data on demographic, health, and lifestyle factors were collected at our research center via interviews, clinical exam- inations, and testing by trained staff. home visits were con- ducted with persons who agreed to participate but were unable or unwilling to come to the center. an injurious fall was defined as hospitalization for or receipt of outpatient care because of a fall (22). international classifi- cation of diseases, tenth revision, discharge diagnoses as- signed from the date of the baseline examination to the last available date (december 31, 2011) were used. these included the external-cause codes w00, w01, w05–w10, and w17– w19: falls on the same level (codes w00, w01, and w18); falls from furniture, wheelchairs, etc. (codes w05–w09); falls from one level to another (e.g., from stairs) (codes w10 and w17); and unspecified falls (code w19). we did not include injurious falls caused by other people or by falling from heights, because these were considered extreme events (e.g., code w12: falling from scaffolding). information on falls was retrieved from the national patient register, which includes data from inpatient care and specialized outpatient care, and from the local outpatient register, which includes data from primary care given in the stockholm county council area (23). outcome status was determined by linking each partici- pant’s personal identification number to the registers. because of the personal identification number, these data are highly reliable (24). previous injurious falls were defined as falls occurring up to 3 years before the baseline examination. information about the vital status of the participants up to december 31, 2011, was obtained from the swedish cause of death registry. we assessed pain characteristics that have been described as important in the assessment of pain by the american geriatrics society, including the location, intensity, and frequency of pain and its interference with daily activities (25). pain characteris- tics were determined with a questionnaire that asked about pain experienced during the previous 4 weeks (26). the presence of pain was assessed with the question, “in the last 4 weeks, have you experienced pain?”. response alternatives were “yes” and “no.” the location of pain was determined with a 9-item ques- tion that ascertained whether the person had pain in the head, neck, back, joints, shoulders/upper extremities, lower extremi- ties/feet, chest, abdomen, or genitals. we classified pain loca- tion by the number of pain sites: no pain, pain at a single location, and pain at 2 or more locations (6, 27). people with pain in their joints were classified as having pain at 2 or more locations. the intensity of pain was assessed with the question, “in the last 4 weeks, how much pain have you had?”. response options were “none,” “very mild,” “mild,” “moderate,” “severe,” and “very severe” (6). in the analyses, we categorized pain intensity as no pain (“none”) or very mild pain, mild-to- moderate pain, and severe or very severe pain. interference with daily activities/conditions was determined via the 6-item question, “in the last 4 weeks, how much 0.01).="" the="" swedish="" national="" study="" on="" aging="" and="" care="" in="" kung-="" sholmen="" was="" approved="" by="" the="" regional="" ethical="" review="" board="" in="" stockholm,="" sweden.="" written="" informed="" consent="" was="" col-="" lected="" from="" participants.="" if="" the="" person="" could="" not="" answer="" (e.g.,="" was="" cognitively="" impaired),="" consent="" was="" obtained="" from="" a="" proxy="" (usually="" a="" close="" family="" member).="" data="" collection="" data="" on="" demographic,="" health,="" and="" lifestyle="" factors="" were="" collected="" at="" our="" research="" center="" via="" interviews,="" clinical="" exam-="" inations,="" and="" testing="" by="" trained="" staff.="" home="" visits="" were="" con-="" ducted="" with="" persons="" who="" agreed="" to="" participate="" but="" were="" unable="" or="" unwilling="" to="" come="" to="" the="" center.="" an="" injurious="" fall="" was="" defined="" as="" hospitalization="" for="" or="" receipt="" of="" outpatient="" care="" because="" of="" a="" fall="" (22).="" international="" classifi-="" cation="" of="" diseases,="" tenth="" revision,="" discharge="" diagnoses="" as-="" signed="" from="" the="" date="" of="" the="" baseline="" examination="" to="" the="" last="" available="" date="" (december="" 31,="" 2011)="" were="" used.="" these="" included="" the="" external-cause="" codes="" w00,="" w01,="" w05–w10,="" and="" w17–="" w19:="" falls="" on="" the="" same="" level="" (codes="" w00,="" w01,="" and="" w18);="" falls="" from="" furniture,="" wheelchairs,="" etc.="" (codes="" w05–w09);="" falls="" from="" one="" level="" to="" another="" (e.g.,="" from="" stairs)="" (codes="" w10="" and="" w17);="" and="" unspecified="" falls="" (code="" w19).="" we="" did="" not="" include="" injurious="" falls="" caused="" by="" other="" people="" or="" by="" falling="" from="" heights,="" because="" these="" were="" considered="" extreme="" events="" (e.g.,="" code="" w12:="" falling="" from="" scaffolding).="" information="" on="" falls="" was="" retrieved="" from="" the="" national="" patient="" register,="" which="" includes="" data="" from="" inpatient="" care="" and="" specialized="" outpatient="" care,="" and="" from="" the="" local="" outpatient="" register,="" which="" includes="" data="" from="" primary="" care="" given="" in="" the="" stockholm="" county="" council="" area="" (23).="" outcome="" status="" was="" determined="" by="" linking="" each="" partici-="" pant’s="" personal="" identification="" number="" to="" the="" registers.="" because="" of="" the="" personal="" identification="" number,="" these="" data="" are="" highly="" reliable="" (24).="" previous="" injurious="" falls="" were="" defined="" as="" falls="" occurring="" up="" to="" 3="" years="" before="" the="" baseline="" examination.="" information="" about="" the="" vital="" status="" of="" the="" participants="" up="" to="" december="" 31,="" 2011,="" was="" obtained="" from="" the="" swedish="" cause="" of="" death="" registry.="" we="" assessed="" pain="" characteristics="" that="" have="" been="" described="" as="" important="" in="" the="" assessment="" of="" pain="" by="" the="" american="" geriatrics="" society,="" including="" the="" location,="" intensity,="" and="" frequency="" of="" pain="" and="" its="" interference="" with="" daily="" activities="" (25).="" pain="" characteris-="" tics="" were="" determined="" with="" a="" questionnaire="" that="" asked="" about="" pain="" experienced="" during="" the="" previous="" 4="" weeks="" (26).="" the="" presence="" of="" pain="" was="" assessed="" with="" the="" question,="" “in="" the="" last="" 4="" weeks,="" have="" you="" experienced="" pain?”.="" response="" alternatives="" were="" “yes”="" and="" “no.”="" the="" location="" of="" pain="" was="" determined="" with="" a="" 9-item="" ques-="" tion="" that="" ascertained="" whether="" the="" person="" had="" pain="" in="" the="" head,="" neck,="" back,="" joints,="" shoulders/upper="" extremities,="" lower="" extremi-="" ties/feet,="" chest,="" abdomen,="" or="" genitals.="" we="" classified="" pain="" loca-="" tion="" by="" the="" number="" of="" pain="" sites:="" no="" pain,="" pain="" at="" a="" single="" location,="" and="" pain="" at="" 2="" or="" more="" locations="" (6,="" 27).="" people="" with="" pain="" in="" their="" joints="" were="" classified="" as="" having="" pain="" at="" 2="" or="" more="" locations.="" the="" intensity="" of="" pain="" was="" assessed="" with="" the="" question,="" “in="" the="" last="" 4="" weeks,="" how="" much="" pain="" have="" you="" had?”.="" response="" options="" were="" “none,”="" “very="" mild,”="" “mild,”="" “moderate,”="" “severe,”="" and="" “very="" severe”="" (6).="" in="" the="" analyses,="" we="" categorized="" pain="" intensity="" as="" no="" pain="" (“none”)="" or="" very="" mild="" pain,="" mild-to-="" moderate="" pain,="" and="" severe="" or="" very="" severe="" pain.="" interference="" with="" daily="" activities/conditions="" was="" determined="" via="" the="" 6-item="" question,="" “in="" the="" last="" 4="" weeks,="" how="">
Answered Same DayJan 30, 2021

Answer To: For this assignment, your instructor will provide you with an epidemiological research article to...

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