Human geneticists interested in the effects of abnormalities in chromosome number often karyotype tissue obtained from spontaneous abortions. About 35% of these samples show autosomal trisomies, but only about 3% of the samples display autosomal monosomies. Based on the kinds of errors that can give rise to aneuploidy, would you expect that the frequencies of autosomal trisomy and autosomal monosomy should be more equal? Why or why not? If you think the frequencies should be more equal, how can you explain the large excess of trisomies as opposed to monosomies?
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