Discussion Board 1 Prompt: You serve on a committee for a charitable foundation that will vote and decide how to fund grant requests for research on specific diseases. This research could lead to...

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Discussion Board 1 Prompt: You serve on a committee for a charitable foundation that will vote and decide how to fund grant requests for research on specific diseases. This research could lead to better understanding of disease mechanisms or new therapies/interventions. The applications for the grants have been narrowed down to 3 choices. Out of these choices, you may only choose one to vote for: 1. Osteogenesis imperfecta 2. Duchenne muscular dystrophy 3. Amylotropic lateral sclerosis Which option will you choose and try to convince others to vote for? There is no perfect choice available and all three choices have strong grant applications. Through this 2-part discussion with your classmates, you will state your choice, explain the disease, and why you chose to vote this way using appropriate and sufficient evidence. Your explanation should include the cause of the disease, impact on the anatomy and physiology of the body, demographics, symptoms, currently available research/treatments, and prognosis. You will respond to your classmates’ posts to convince them why they should vote the same way as you. You may also be convinced by a classmate to switch your initial vote. In other words, you need to know why your choice is the best choice and why the other choices would not be. Remember, no answer is one hundred percent correct so you are not saying that others are wrong, but instead why your choice is optimal based on evidence. Initial Post (Worth up to 70 points) · Length: 250-500 words · 12pt font · All sources (3 required) must be properly cited (see APA source citation below) · State and explain your choice. When stating the evidence, consider the challenges that others may have to your evidence and how you could counter those respectful challenges. APA Source Citation You must use at least 3 reputable scientific references to support your post (not including your textbook- if you use your textbook, you must also cite it). Reputable sources= peer reviewed scientific journal articles, accredited websites, or books. Google, Wikipedia, etc. are not acceptable sources. Your information must be credible, accurate, and well supported by evidence. The best sources of information are the research journals and the books as well as webpages maintained by professional societies and organizations. Search for articles and academic material should start with the electronic databases of libraries such as FTCC’s Paul H. Thompson Library (opens new window), PubMed (opens new window) or other such resources. When in doubt about material, use CARS checklist (opens new window) to see if it can be used in discussions and writings. You must cite all sources, both as and work cited and in-text. Citation format must be APA (See examples below). If you need more information, visit the Purdue Owl Writing Lab (opens new window) for instructions on proper formatting. Works Cited References Website Format Lastname, F. M. (Year, Month Date). Title of page. Site name. URL Example Price, D. (2018, March 23). Laziness does not exist. Medium. https://humanparts.medium.com/laziness-does-not-exist-3af27e312d01 Scientific Journal Articles Format Author, A. A., Author, B. B., & Author, C. C. (Year). Title of article. Title of Periodical, volume number(issue number), pages. https://doi.org/xx.xxx/yyyy Print Journal Example Scruton, R. (1996). The eclipse of listening. The New Criterion, 15(3), 5–13. Electronic Journal Example Baniya, S., & Weech, S. (2019). Data and experience design: Negotiating community-oriented digital research with service-learning. Purdue Journal of Service-Learning and International Engagement, 6(1), 11–16. https://doi.org/10.5703/1288284316979 Book Format Author, A. A. (Year of publication). Title of work: Capital letter also for subtitle. Publisher Name. Example Malory, T. (2017). Le morte darthur (P. J. C. Field, Ed.). D. S. Brewer. (Original work published 1469-70) In-Text Citations (must correspond to reference in works cited section) When paraphrasing format= Author-Date Example: (Jones, 1998) When Quoting= Author-Date-Page Number(s) Example: (Jones, 1998, p. 199) or (Jones, 1998, pp. 199–201) Responses (Worth up to 30 points) Respond to at least 2 classmate’s discussion submissions. · Each response must be 150-200 words (12pt font)! · Evaluate their post. You are either adding more evidence to a post that made the same choice as you or challenging another choice (respectfully) with evidence. · Offer questions or responses to what is said. Offer Research that backs or refutes a point being made (“Good Jobs”, or “I agree” are NOT allowed as your response!!). Your response should add to the body of knowledge in the class. Discussion Board Rubric Use the following rubric to write your post AND to respond to your peers. I will also use this same rubric to grade your post and responses! · Initial Post= 70pts · Explanation= 40pts · 40pts= Clear, strong, and supported position for the chosen disease with a thorough explanation of why this disease should receive funding. Includes 100% of the following: cause of the disease, impact on the anatomy and physiology of the body, demographics, symptoms, currently available research/treatments, and prognosis. · 30pts= Clear, supported position for the chosen disease with a thorough explanation of why this disease should receive funding. Includes 75% of the following: cause of the disease, impact on the anatomy and physiology of the body, demographics, symptoms, currently available research/treatments, and prognosis. · 25pts= Position for the chosen disease is stated with a brief explanation of why this disease should receive funding. Includes 50% of the following: cause of the disease, impact on the anatomy and physiology of the body, demographics, symptoms, currently available research/treatments, and prognosis. · 15pts= Position for the chosen disease is stated without explanation of why this disease should receive funding. Includes at least 25% of the following: cause of the disease, impact on the anatomy and physiology of the body, demographics, symptoms, currently available research/treatments, and prognosis. · 10pts= Clear position for the chosen disease is not stated. Includes less than 25% of the following: cause of the disease, impact on the anatomy and physiology of the body, demographics, symptoms, currently available research/treatments, and prognosis. · 5pts= Explanation is unclear, incomplete, and not supported. · 0pts= No explanation. · Sources= 15pts · 15pts= The required number of sources are provided (minimum of 3, not including textbook). All sources used for quotes, statistics, and facts are credible and cited correctly. Citations are both in-text and in the works cited section. · 12pts= The required number of sources are provided (minimum of 3, not including textbook). Most sources used for quotes, statistics, and facts are credible and cited correctly. Citations are either only in-text or in the works cited section, but not both. · 10pts= Only 2 sources are provided. Not all sources used are credible and/or not all are cited correctly. Citations are both in-text and in the works cited section. · 7pts= Only 2 sources are provided. Not all sources used are credible and/or not all are cited correctly. Citations are either only in-text or in the works cited section, but not both. · 5pts= Only 1 source is provided. Not all sources used are credible and/or not all are cited correctly. Citations are both in-text and in the works cited section. · 3pts= Only 1 source is provided. Not all sources used are credible and/or not all are cited correctly. Citations are either only in-text or in the works cited section, but not both. · 0pts= Sources are not cited at all, are not credible, and/or are not cited correctly. · Length/ Grammar/ Spelling = 15pts · 15pts= Post is of required length (250-500 words). Less than 10% of errors in grammar or spelling that distract the reader from the content. · 12pts= Post is approximately 75% of the required length. 10% of errors in grammar or spelling that distract the reader from the content. · 10pts= Post is approximately 50% of the required length. 30% of errors in grammar or spelling that distract the reader from the content. · 7pts= Post is approximately 25% of required length. 50% of errors in grammar or spelling that distract the reader from the content. · 5pts= Post less than 25% of the required length. 70% of errors in grammar or spelling that distract the reader from the content. · 3pts= Post is less than 10% of the required length. 90% of errors in grammar or spelling that distract the reader from the content. · 0pts= No post. · Responses= 30pts · 30pts= Two responses and each meets the required length (150-200 words). Comments add to the classroom discussion and are thoughtful, reflective, and respectful of other’s postings. · 25pts= Two responses and only one meets the required length (150-200 words). Comments add to the classroom discussion and are thoughtful, reflective, and respectful of other’s postings. · 20pts= Two responses, but neither meets the required length (150-200 words). Comments add to the classroom discussion and are thoughtful, reflective, and respectful of other’s postings · 15pts= Only one response is posted, but meets the required length (150-200 words). Comments add to the classroom discussion, but only minimally reflect the topic or the other student’s posting. · 10pts= Only one response is posted and it does not meet the required length (150-200 words). Comments are not reflective of the topic or other student’s posting. · 5pts= Only one response is used and/or shows a minimum effort in reading and understanding other student’s post. (e.g. "I agree with Bill") · 0pts= No responses. 2
Answered Same DayJun 06, 2021

Answer To: Discussion Board 1 Prompt: You serve on a committee for a charitable foundation that will vote and...

Dr. Sulabh answered on Jun 06 2021
139 Votes
OSTEOGENESIS IMPERFECTA        1
Title: Osteogenesis imperfecta
Discussion
The cause of the disease
“Osteogenesis imperfecta” is an
autosomal dominant disease that occurs due to the presence of the mutations in the genes named COL1A1 and COL1A2. These genes have the function of forming the network of the type-I collagen in the body (Medline Plus, 2020). Collagen is essential for providing structure, rigidity, and strength to the body. The bones become weak, fragile, and brittle. There are different types of this disease like I, II, III, IV, V, VI, VII, and VIII. In a rare condition, this disease also occurs due to a recessive mutation in a single allele or copy of a gene and normally occurs in types ranging from VI to XVIII (Medline Plus, 2020).
 Impact on the anatomy and physiology of the body
The body loses the structural framework, rigidity, and strength due to a defect in the synthesis, formation and arrangement of collagen that supports the various organs and tissues of the body. The lack of proper formation of collagen causes specific deformities in the legs with the formation of a bent shape (Osteogenesis Imperfecta Overview, 2021). There are deformities in the formation of the cranium and mandible bones in a patient (Marom et al., 2020).
Demographics
The frequency of the...
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