NEUR3003 Marking rubric 2019 Literature Review Task In consultation with their supervisors, students should define a specific area of research on which to base their reading and then prepare a...

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NEUR3003 Marking rubric 2019 Literature Review Task In consultation with their supervisors, students should define a specific area of research on which to base their reading and then prepare a 2000-word literature review on this area. Assessment criteria for Final research essay/report Essays will be assessed by supervisors or another suitable academic using the marking sheet below, against Faculty grade descriptors in relation to each of the following aspects. (1) CLARITY OF PURPOSE: Does review have a central theme or hypothesis and does the title and abstract clearly and accurately summarise that theme? (20%) (2) INTEGRATION: Does the review intelligently integrate the findings of multiple research papers in a logical sequence so as to develop the central theme or working hypothesis of the review? (20%) (3) SCIENTIFIC DEPTH: Does the student convincingly explain the nature of the evidence from the individual papers upon which her/his key conclusions are based? (20%) (4) APPROPRIATE STYLE and QUALITY CONTROL: The essay should follow the style of a review article in a scientific journal, should be type written using formal English. Is the text unambiguous and easy to read? Is it largely free of typographical and spelling errors? Is the source of evidence properly cited in the text with the citations all listed at the end in a consistent and appropriate format (20%) (5) CONCLUSIONS AND SIGNIFICANCE: How well are the conclusions supported by the evidence presented? How convincingly do the conclusions address the issue/hypothesis that was defined by the title and abstract? (20%) These criteria will be assessed with reference to the grade descriptors: 50-64 PASS: The work addresses the issues posed by the task; the level of consideration is adequate in the context of the aims, objectives and expected outcomes of the unit of study, but lacks a demonstrated depth of understanding, or suggests lack of understanding of some facts. 65-74 CREDIT: The work is clearly presented, thorough and addresses the issues posed by the task at a level of consideration consistent with the aims, objectives and expected outcomes of the unit of study. The work demonstrates a good grasp of the facts. 75-84 DISTINCTION: The work meets the criteria for a CREDIT, but in addition is well written, and demonstrates understanding of the subject matter as described by the aims, objectives and expected outcomes of the unit of study, at the highest level. 85-100 HIGH DISTINCTION: The work meets the criteria for a DISTINCTION, but in addition demonstrates inquiry into, understanding of and presentation of the subject matter significantly beyond what is expected in the context of the aims, objectives and expected outcomes of the unit of study. A marking rubric for the final report/essay follows 1 Marking Rubric for Literature Review for Student name: Total (/100%): Exemplary Very Good Good Acceptable Not acceptable HD D C P CLARITY OF PURPOSE: Does review have a central theme or hypothesis and do the title and abstract (1250 character limit) clearly and accurately summarise that theme? 20 19 17 16 14 12 11 10 INTEGRATION: Does the review intelligently integrate the findings of multiple research papers in a logical sequence so as to develop the central theme or working hypothesis of the review? 20 19 17 16 14 12 11 10 SCIENTIFIC DEPTH: Does the student convincingly explain the nature of the evidence from the individual papers upon which her/his key conclusions are based? 20 19 17 16 14 12 11 10 APPROPRIATE STYLE and QUALITY CONTROL: The essay should follow the style of a review article in a scientific journal, should be type written using formal English. Is the text unambiguous and easy to read? Is it largely free of typographical and spelling errors? Is the source of evidence properly cited in the text with the citations all listed at the end using the Harvard Style? 20 19 17 16 14 12 11 10 CONCLUSIONS AND SIGNIFICANCE: How well are the conclusions supported by the evidence presented? How convincingly do the conclusions address the issue/hypothesis that was defined by the title and abstract? 20 19 17 16 14 12 11 10 Disruption of TDP-43 normal functions is one of the ways in which neurodegeneration is thought to occur in ALS and FTD and there are many primary research articles that provide evidence of this.  So, the central argument of your review would be is it loss of nuclear TDP-43 or gain of cytoplasmic TDP-43 that is causing disease? And present both sides using primary research articles to provide evidence for each argument. As discussed at the tutorial last week the body of your review article should include 2-5 subheadings. Loss of nuclear TDP-43 - what are the normal functions of TDP-43 within the nucleus and how do these become disrupted in ALS/FTD Cytoplasmic accumulation of TDP-43 - post-translational modifications of TDP-43 e.g. ubiquitination, phosphorylation, fragmentation - how this effects the localisation and accumulation of TDP-43, sequestration of TDP-43 into stress granules and discuss how this may lead to disease by disrupting normal cellular functions. · Whether tdp-43 mediated neuronal loss is caused by toxic gain of function of cytoplasmic aggregates or by a loss of its normal function in the nucleus What triggers the cytoplasmic accumulations and nucleus depletion of tdp-43 in patients without pathogenic mutations
Answered 6 days AfterOct 21, 2021

Answer To: NEUR3003 Marking rubric 2019 Literature Review Task In consultation with their supervisors, students...

Neha answered on Oct 28 2021
115 Votes
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LOSS OF NUCLEAR TDP-43 OR GAIN OF CYTOPLASMIC TDP-43 IN ALS: A DETAILED OVERVIEW OF FRONTOTEMPORAL DEMENTIA AND ALS
This title doesn’t say anything about td
p-43 and that is the main thing??
LITERATURE REVIEW
For the plan:
1. Please give me a title in the format like the sample
2. I need a short para of the theme of what you will discuss in the article – this will be like the first para in the sample that’s under the title.
3. Subheadings can you word them all better like the sample ones, please
4. Under each subheading, can you list at least 6 articles each subheading.
5. You need to talk about the main things you will discuss in each subheading.
^ so these are the points I said to cover. I specified these when the first time you didn’t do it properly, so gave these but this time you went in the total different direction.
Also with the subheadings you went way off to what I was even saying. You clearly didn’t understand anything. I don’t get why ur talking about symptoms and all the other subheadings u used, it doesn’t’ not make sense at all where you got that from based of the topic I gave u?????
The things you wrote as well is not analysis, you are just getting stuff from online and making them into sentences, it doesn’t say anything clearly cause u talk about once thing at once and another later. Some sentences don’t even make sense.
This is for all the stuff written below^
And if you see I asked for the articles and what you will discuss in them. But you clearly missed that.
Introduction
    Amyotrophic lateral sclerosis (ALS) is a disease that is caused by devastation of motor degeneration and so far, it has not...
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