Name______________________ KU ID __________ Date_________ References MSDA Print File :E:\DATA XXXXXXXXXXPROPRANOLOL-7.D Operator : Acquired : 16 Jan XXXXXXXXXX:07 using AcqMethod PROPAUTO.M Instrument...

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The assignment is just answering 4 questions in the document Proforma, to answer it I have attached the results to answer the questions.Thanks you.


Name______________________ KU ID __________ Date_________ References MSDA Print File :E:\DATA\150120-PROPRANOLOL-7.D Operator : Acquired : 16 Jan 2020 14:07 using AcqMethod PROPAUTO.M Instrument : GC MS 1 Sample Name: Misc Info : Vial Number: 1 2.50 3.00 3.50 4.00 4.50 5.00 5.50 6.00 6.50 7.00 7.50 8.00 8.50 9.00 9.50 10.00 10.50 11.00 11.50 12.00 12.50 13.00 13.50 1000000 2000000 3000000 4000000 5000000 6000000 7000000 8000000 9000000 1e+07 Time--> Abundance TIC: 150120-PROPRANOLOL-7.D 7.70 11.25 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 0 50000 100000 150000 200000 250000 300000 350000 400000 450000 m/z--> Abundance Scan 1494 (10.868 min): 05-02-2020group2.D 149 167 57 43 71 279 11383 97 132 207 261179 193 221 249233 355303 446417390341291 319 429404 458371 484 MSDA Print Library Searched : C:\Database\NIST02.L Quality : 96 ID : 1-Naphthalenol 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 0 1000 2000 3000 4000 5000 6000 7000 8000 9000 m/z--> Abundance Scan 955 (7.698 min): 150120-PROPRANOLOL-7.D 144 115 89 63 7239 51 1269879 135 281195 207 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 0 1000 2000 3000 4000 5000 6000 7000 8000 9000 m/z--> Abundance #19581: 1-Naphthalenol 144 115 897258 6551 98 12610579 OH MSDA Print Library Searched : C:\Database\NIST02.L Quality : 97 ID : Propranolol 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 0 1000 2000 3000 4000 5000 6000 7000 8000 9000 m/z--> Abundance Scan 1559 (11.251 min): 150120-PROPRANOLOL-7.D 72 115 144 2592155643 128 24410289 157 183170 198 281228 341 355295 315 429415 446391 475 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 0 1000 2000 3000 4000 5000 6000 7000 8000 9000 m/z--> Abundance #93864: Propranolol 72 30 115 144 215 25956 43 100 128 244183157 86 170 198 O OH NH
Answered Same DayFeb 07, 2021

Answer To: Name______________________ KU ID __________ Date_________ References MSDA Print File :E:\DATA...

Anju Lata answered on Feb 14 2021
138 Votes
Name______________________ KU ID __________ Date_________
(
At Peak
72- Due to C16 H21 NO2

At 115- M+= C6 H13NO+
At 144- M+= C6H13 NO
At 215- M+= C3H6-H
At 244- M+= CH3
At 259- M+
The two most abundant peaks in spectrum= 72 and 115
)
(
The identified impurity is 1-Naphthalenol
. Two Most abundant peaks
for impurity
are 144 and 115
M/
Z

259
----
M/Z 144 -----
M/Z 115
)
(
Possible source for the contaminant may be
(a) Manufacturing
process or

(b) Degradation of the pharmaceutical product
Contaminants may appear in manufactured drugs through the raw...
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