Answer To: MTE XXXXXXXXXXResearch Seminar Essay Coordinator: Dr. Di Leva Gianpiero (Module leader) XXXXXXXXXX...
Asif answered on Jul 01 2021
RESEARCH SEMINAR ESSAY
Abstract
In microfluidics, 3D printing represents the third revolution. 3D printing technology is used to produce a device capable of improving interior contact areas and changing the dynamics of water. It may be used for cancer testing, neurophysiology, drug testing, and remote monitoring of patients. From research to industry, the therapeutic uses of 3D printing advance quickly. In the fields of physiological research, drug administration, and structural development, this article promises numerous benefits. 20 active or experimental research is presently underway employing 3D components. The study has proven successful as numerous 3D printed technologies have been granted FDA clearance. The most popular 3D printing process is fused deposition modelling (FDM). Aerospace technology, car, bio-medical, intelligent home, workplaces, and coaching aid are increasingly used using FDM technology. It's fantastic for unbelievably easy usage, easy operation, and minimal use. Sculpted uses DLP technology for Silver and Brass 3D printing to produce discreet capsules, with smooth surfaces on the outside. Theophylline has been a model research drug.
Through the ability to produce prototypes even without the need for costly tools, 3D printing helps education. Students may imitate museum artifacts such as fossils and cultural monuments, preventing damage to delicate classroom collections. In 3D printing, the potential for producing customized prostheses for patients is outstanding. In certain third-world countries, prostheses are not even an option. Bioprinters enable artificial organs to be produced 3D to resolve organ failure concerns.
Table of Contents
Introduction 4
Discussion 4
3D printing and microfluidic devices as promising alternatives for fabrication techniques. 4
3D-printed microfluidic devices as cell tissue culture devices 5
Diversity of 3D printing techniques 7
Applications of 3D printing techniques 10
Microfluidic device 12
Conclusion 14
Reference List 15
Introduction
There has been considerable interest in additive or 3D printing in contemporary years, as it is more widely known, and this is referred to as a third revolution. 3D printing technology is utilized to manufacture a microfluidic device that can enhance internal contact areas and alter water dynamics (Chen et al., 2020). 3D printing is capable of changing the field of microfluidics considerably. The capacity to build a full microfluidic device in one single movement from a computer simulation has clear charms, but it is also the possibility, using existing techniques, to develop three-dimensional frameworks that give unprecedented, if not inconceivable microfluidic capabilities. Detection limits were also found for PTB biomarkers in the high picomolar to the low nanomolar range for microchip electrophoresis in 3D printed microfluidic equipment (Beauchamp et al., 2019). Commercial 3D printers that can manufacture objects from a few micrometres to several centimetres start to challenge the soft lithograph as a prototype research technique to the manufacturing industry.
Discussion
3D printing and microfluidic devices as promising alternatives for fabrication techniques.
Microfluidics is a prosperous subject that requires a significant amount of biochemical and clinical applications such as cancer testing, neurophysiology, drug testing, and remote patient monitoring analysis. The platform for the fabrication and construction of inorganic and polymeric materials has emerged as a useful and in some cases unique platform for microfluidics (Bressan et al., 2019). Nevertheless, manufacturing microfluidic technology is frequently difficult, moment and sterile conditions need high costs. Three-dimensional (3D) printing is a potential solution, not just in enabling rapid design iterations during the stage of development but also in managing the risks associated with technological mechanisms, high - functioning, upkeep as well as physical space, for traditional technologies like lithography and PDMS glass bonding. The lowest-cost 3D printing method has been founded on Fusion Deposition Modelling (FDM) over the past number of years in microfluidics. Nevertheless, clear windows for optical detection are inadequate in resolution and ability to penetrate (Alizadehgiashi et al., 2018). Latest developments in 3D printing technologies have enabled the production, through single attempts, fast and economic procedures, of extremely complicated microfluidic types of equipment which make microfluidics more user-friendly.
Image 1: 3D printing and microfluidic devices
Source: (Alizadehgiashi et al., 2018)
3D-printed microfluidic devices as cell tissue culture devices
3D printing plays a major role, including but is not restricted to, cultural systems and implanted devices, for different biomedical research applications. Recent uses of therapeutically driven research 3D printing technology, concentrating in particular on buildings afterward integrated into cell production (Mehta and Rath, 2021). This technique applies to prescription medicines, frameworks for cultivating bioreactors, acellular scaffolding, diagnostic methods, and chip organ systems. Without 3D printing, it is not feasible to emphasize the technical developments: when traditional production techniques are difficult for research goals to be demonstrated. More subsequently, 3D printing was used to produce moulds for softer lithograph, only other phase which frequently still requires a clean-room environment, for microfluidic PDMS devices to be quickly prototyped forward. The therapeutic uses of 3D printing are advancing fast from research to manufacturing and will surely remain growing as the number of treatments is growing. This paper promises several uses in the field of physiological research, pharmacological administration, and structural enhancements. The development of 3D printing technology promises that the biological research community may access microfluidic organ-in-chip technologies more easily (Ferraz et al., 2020). 3D printing quickly progressed to a broadly accessible desktop manufacturing technique from an innovative invention. In the context of clinical applications, fast prototyping offers technologists, clinicians, and scientists’ great freedom and the chance to work together to address medical issues quickly. There are currently 20 ongoing or experimental studies using 3D components, including metal implant materials, atrial fibrillation gadgets, heart monitors, as well as sleeping aponia covers. Researchers are continually interested in the area of how to quickly build microfluidic devices utilizing software modules (Ong et al., 2017). This clinical study is becoming successful since FDA permission has been given to several 3D printing technologies. 2 These gadgets remain mainly acellular, though. 3D printing has an extensive clinical appeal in one day...