Reagents 1. excess NABH4 Trimethylsilyl chloride / triethylamine a h 1. Li(CH3)2Cu 2. H30* e 2. Hзо* b 1. 1 еq. NaBH4 2. Hзо* CrO3 / H30* f 1. CH3MGB / dry ether 2 H30* i 1. LIAIH4 Dess-Martin...


How might you carry out the following selective transformations? (Note that a protection step may be required, and recall that aldehydes are more reactive than ketones toward nucleophilic addition.)


Reagents<br>1. excess NABH4<br>Trimethylsilyl chloride /<br>triethylamine<br>a<br>h<br>1. Li(CH3)2Cu<br>2. H30*<br>e<br>2. Hзо*<br>b<br>1. 1 еq. NaBH4<br>2. Hзо*<br>CrO3 / H30*<br>f<br>1. CH3MGB / dry ether<br>2 H30*<br>i<br>1. LIAIH4<br>Dess-Martin periodinane<br>in CH2CI2<br>g<br>HOCH2CH2OH / HCI<br>2. Hзо*<br>d<br>aqueous HCI<br>Он<br>a)<br>H.<br>H.<br>но снз<br>b)<br>

Extracted text: Reagents 1. excess NABH4 Trimethylsilyl chloride / triethylamine a h 1. Li(CH3)2Cu 2. H30* e 2. Hзо* b 1. 1 еq. NaBH4 2. Hзо* CrO3 / H30* f 1. CH3MGB / dry ether 2 H30* i 1. LIAIH4 Dess-Martin periodinane in CH2CI2 g HOCH2CH2OH / HCI 2. Hзо* d aqueous HCI Он a) H. H. но снз b)

Jun 11, 2022
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