You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a...


You are studying a disease caused when the gene called BMP5 is not transcribed in osteoblasts. All other genes are transcribed normally. To investigate why BMP5 is not transcribed, you create a reporter transgene by putting GFP under the control of theBMP5 enhancer found indiseased osteoblasts.You put this reporter transgene into a normal, healthy osteoblast.


If the healthy osteoblast with your GFP-reporter transgene DOES turn green (GFP is expressed), what is one possiblegenetic reason that BMP5 is not being expressed in people with this disease?  Explain your answer



Jun 11, 2022
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