An 83-year-old man with a history of congestive heart failure is taking a number of prescription medications, including psyllium (Metamucil), digoxin (Lanoxin), phenytoin (Dilantin), and cimetidine...

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A Case Study
Relevant assessment priorities
When assessing a potential interaction, the significant priorities are: clinical implications, probability, and severity of the interactions, evidence in favour of interaction; and patient characteristics. Studies state that the severity of the interactions should be determined primarily by the benefit/risk of utilising the drug pair concurrently. Scholars state taking into account the management burden of the interactions, the planned surveillance, and the provider's knowledge of the interactions (Grover et al. 2021). Additionally, the timeline of administration is crucial for determining the likelihood that an interaction will occur. In regards to study design, randomised trials provide high-standard evidence while observational studies provide poor quality evidence. The signal becomes more valuable and enables the health practitioner to only see notifications pertinent to the sick person at hand by retrieving patient-specific parameters from the...