1. A 26-year-old m an presented to the em ergency departm ent w ith sudden onset of fever (101.1°F, 38.5°C), oliguria, and a skin rash. The m an had been receiving system ic pharm acotherapy for prim...

1. A 26-year-old m an presented to the em ergency departm ent w ith sudden onset of fever (101.1°F, 38.5°C), oliguria, and a skin rash. The m an had been receiving system ic pharm acotherapy for prim ary syphilis. Laboratory ndings showed eosinophiluria and proteinuria. Further exam s led to the Questions: VIII-1 Bacterial Cell Wall Synthesis Inhibitors 403 diagnosis of drug-induced tubulointerstitial nephritis. Which of the follow ing antibiotics m ost likely caused the patient’s disease? A. Penicillin G B. Cefepim e C. Rifam pin D. Nafcillin E. Trim ethoprim -sulfam etoxazole