1. A 33-year-old wom an recently diagnosed w ith severe m icrocytic anem ia felt uneasy and becam e agitated and ushed soon after the rst intravenous injection of an antianem ic drug. She also...

1. A 33-year-old wom an recently diagnosed w ith severe m icrocytic anem ia felt uneasy and becam e agitated and ushed soon after the rst intravenous injection of an antianem ic drug. She also complained of palpitations, coughing, urticaria, and di culty in breathing. Within 5 m inutes, cardiovascular collapse developed. Which of the follow ing drugs m ost likely caused the patient’s syndrom e? A. Leucovorin B. Ferrous sulfate C. Iron dextran D. Cyanocobalam in E. Filgrastim F. Sargramostim 2. A 51-year-old m an undergoing am bulatory hem odialysis for end-stage renal disease had been receiving erythropoietin for norm ochrom ic norm ocytic anem ia. A blood analysis showed the following results: red blood cell count 4.4 × 106/mm3 (norm al, m ale 4.3-5.9 × 106/mm3), m ean corpuscular volum e 98 fL (norm al 80-100 fL), hem oglobin 14 g/dL (norm al, m ale > 13.5 g/dL). The patient was m ost likely at greater risk of w hich of the follow ing drug-related adverse e ects? A. Throm botic com plications B. Hypotension C. Angioedem a D. Hypokalem ia E. Adynam ic ileus