1. A 41-year-old m an cam e to the clinic com plaining of an extensive rash, w hite plaquelike lesions in his m outh, dry eyes, hyperpigm entation of the tissues surrounding the eyes, and diarrhea....

1. A 41-year-old m an cam e to the clinic com plaining of an extensive rash, w hite plaquelike lesions in his m outh, dry eyes, hyperpigm entation of the tissues surrounding the eyes, and diarrhea. Three m onths earlier, the m an, w ho was su ering from chronic m yelogenous leukem ia, underwent an allogeneic bone m arrow transplant from his sister. He was successfully treated for his acute graft-versus-host disease and had no m ajor health problem s after that disease. W hich of the follow ing t wo-drug com binations would represent an appropriate im m unosuppressive pharm acotherapy for the patient at this tim e? A. Prednisone and cyclosporine B. Cyclosporine and erythromycin C. Cyclophospham ide and doxorubicin D. Vinblastine and prednisone E. Doxorubicin and vinblastine