1. A 41-year-old wom an collapsed at hom e and was brought to the em ergency departm ent. Her husband stated she had com plained recently of severe abdom inal cram ping, nausea, vom iting, and...

1. A 41-year-old wom an collapsed at hom e and was brought to the em ergency departm ent. Her husband stated she had com plained recently of severe abdom inal cram ping, nausea, vom iting, and diarrhea. Vital signs on adm ission were tem - perature 103°F (39.4°C), pulse 134 bpm , blood pressure 85/52 m m Hg, respirations 28/m in. Physical exam ination showed a critically ill patient w ith an abdom inal erythem atous indurated area below the um bilicus and an 8-m m (0.31-inch) central ulcer. A uorescent antibody test of a specim en from the ulcer identi ed group A streptococci. Which of the follow ing pairs of drugs would be m ost appropriate for the em ergency treatm ent of this patient? A. Penicillin G and clindamycin B. Tobramycin and m etronidazole C. Chloram phenicol and tetracycline D. Erythromycin and am ikacin E. Piperacillin and aztreonam