1. A 42-year-old m an was seen in the clinic w ith general m alaise, fever (102.5°F, 39.2°C), cough, and dyspnea. Further exam s led to the diagnosis of acute bronchitis. Which of the follow ing enzym...

1. A 42-year-old m an was seen in the clinic w ith general m alaise, fever (102.5°F, 39.2°C), cough, and dyspnea. Further exam s led to the diagnosis of acute bronchitis. Which of the follow ing enzym es was prim arily involved in the patient’s in am m atory disease? A. Creatinine kinase B. Cyclooxygenase-2 C. 5-lipoxygenase D. Lactic dehydrogenase E. 12-lipoxygenase F. Cyclooxygenase 2. A 13-year-old girl com plained to her physician of painful m enstruation accom panied by headache and nausea. She underwent m enarche 6 m onths earlier, and dysm enorrhea had occurred since then. The physician prescribed ibuprofen to be started on the day prior to the expected start of m enstruation. Inhibition of synthesis of w hich of the follow ing endogenous com pounds m ost likely m ediated the therapeutic e ect of ibuprofen in the patient’s disorder? A. Magnesium B. Nitric oxide C. Prostaglandin E2 D. Epinephrine E. Prostaglandin I2