1. A 45-year-old alcoholic wom an, brought to the em ergency departm ent by her husband, was disoriented, com bative, and com plained of headache, vertigo, and “ringing in my ears.” The husband...

1. A 45-year-old alcoholic wom an, brought to the em ergency departm ent by her husband, was disoriented, com bative, and com plained of headache, vertigo, and “ringing in my ears.” The husband reported that she recently said she wanted to com m it suicide. Vital signs were tem perature 103.8°F, pulse 108 bpm , respirations 6/m in, blood pressure 85/60. Pertinent lab data on adm ission were arterial blood pH 7.25, creatinine 2.2 m g/dL (norm al 0.9-1.2 m g/dL), bicarbonate 18 m Eq/L (norm al 22-26 m Eq/L), glucose 170 m g/dL (norm al 70-110 m g/dL). Arterial blood gases were Pa CO2 48 m m Hg (norm al 35-45 P a CO2), Pa O2 75 m m Hg (norm al > 80 Pa O2). Which of the follow ing drugs m ost likely caused the patient’s poisoning? A. Ethanol B. Celecoxib C. Ibuprofen D. Propranolol E. Aspirin F. Diphenhydramine