1. A 46-year-old m an recently diagnosed w ith a duodenal ulcer started a treatm ent that included daily sucralfate. Which of the follow ing m echanism s m ost likely m ediates the therapeutic e cacy...

1. A 46-year-old m an recently diagnosed w ith a duodenal ulcer started a treatm ent that included daily sucralfate. Which of the follow ing m echanism s m ost likely m ediates the therapeutic e cacy of the drug in the patient’s disease?Questions: VI-2 Drugs for Gastrointestinal Disorders 343 A. Acting as a barrier to acid by binding to necrotic ulcer tissue B. Reacting w ith gastric hydrochloric acid to form salt and water C. Inhibiting hydrochloric acid secretion D. Stim ulating bicarbonate secretion by antral parietal cells E. Exerting a bactericidal e ect against Helicobacter pylori