1. A 57-year-old m an recently diagnosed w ith m ild rheum atoid arthritis com plained to his physician of joint pain despite ongoing therapy w ith ibuprofen. The m an was a heavy sm oker and had a...

1. A 57-year-old m an recently diagnosed w ith m ild rheum atoid arthritis com plained to his physician of joint pain despite ongoing therapy w ith ibuprofen. The m an was a heavy sm oker and had a history of chronic bronchitis w ith frequent acute exacerbations usually treated w ith antibiotics. The physician decided to add a disease-m odifying antirheum atic drug (DMARD) to the treatm ent. Which of the follow ing drugs would be m ost appropriate for the patient at this tim e? A. Le unom ide B. Hydroxychloroquine C. Rituxim ab D. Etanercept E. Azathioprine