1. A 59-year-old wom an com plained to her physician of persistent heartburn. She had been taking ibuprofen for osteoarthritis of the right hip for the past 2 m onths. She refused to stop the m...

1. A 59-year-old wom an com plained to her physician of persistent heartburn. She had been taking ibuprofen for osteoarthritis of the right hip for the past 2 m onths. She refused to stop the m edication, w hich she said was very good for her pain. The physician prescribed another drug, to be taken together w ith ibuprofen, to prevent peptic ulcer form ation. Which of the follow ing actions m ost likely contributed to the preventive e ect of the prescribed drug? A. Binding to necrotic ulcer tissue, acting as a barrier for acid and pepsin B. Blockade of m uscarinic M3 receptors on gastric parietal cells C. Blockade of gastrin receptors on gastric parietal cells D. Stim ulation of bicarbonate and m ucus secretion by super cial epithelial cells E. Bactericidal e ect against Helicobacter pylori