A 2-day-old neonate exhibits convulsions. Imaging studies disclose mild hydrocephaly, as well as areas of calcification in periventricular areas and in the brain stem. The neonate is started on...

A 2-day-old neonate exhibits convulsions. Imaging studies disclose mild hydrocephaly, as well as areas of calcification in periventricular areas and in the brain stem. The neonate is started on broad-spectrum antibiotics but dies within 2 days. Examination of the brain at autopsy reveals pink intranuclear inclusions in Purkinje cells. Which of the following is the most likely etiology of cerebral calcification and convulsions in this neonate?

(A) Cryptococcus neoformans

(B) Cytomegalovirus

(C) Human immunodeficiency virus

(D) Poliovirus

(E) Toxoplasma gondii