A 68-year-old woman complains of difficulty getting out of a chair. On examination, the patient shows reduced facial expression, a resting tremor, cogwheel rigidity, and bradykinesia (slowness of...

A 68-year-old woman complains of difficulty getting out of a chair. On examination, the patient shows reduced facial expression, a resting tremor, cogwheel rigidity, and bradykinesia (slowness of voluntary movements). The patient dies of congestive heart failure 10 years later. Microscopic examination of brain tissue at autopsy is shown in the image. The spherical, eosinophilic inclusions in the cytoplasm of this pigmented neuron are composed of which of the following proteins?

(A) b-Amyloid

(B) Polyglutamine

(C) PrPsc

(D) a-Synuclein

(E) Tau