Step 3: Critical Appraisal of Evidence (Initial Thoughts) (25 points) Create an annotated bibliography on a minimum of five empirical research studies that resulted from this search. Include the...

Running Head: PICOT ANALYSIS        1
PICOT ANALYSIS             3
Name of the Student
Course Name
College or University Name
Name of the Tutor/Professor
Annotated Bibliography
In “PICOT” , P means patient problem, I means intervention, C means comparison or control, O means the outcome and T means the time in hours.
1.Bhaskar, S., Stanwell, P., Cordato, D., Attia, J., & Levi, C. (2018). Reperfusion therapy in acute ischemic stroke: dawn of a new era?. BMC Neurology, 18(1). https://doi.org/10.1186/s12883-017-1007-y
This study aimed to compare the treatment of patients with tissue plasminogen activator drug within 4.5 hours and then comparing the reperfusion therapy till 6-8 hours. The results indicate that the therapy performed within 4.5 hours is much more beneficial as compared to the delayed time interval therapy with surgical interventions.
2. Cheng, N., & Kim, A. (2015). Intravenous Thrombolysis for Acute Ischemic Stroke Within 3 Hours Versus Between 3 and 4.5 Hours of Symptom Onset. The Neurohospitalist, 5(3), 101-109. https://doi.org/10.1177/1941874415583116
According to Cheng & Kim (2015), the purpose of the study is to analyze the time interval during which the intravenous tissue plasminogen activator therapy is effective for treating patients suffering from acute ischemic stroke. The hypothesis is that if this therapy is provided...